ISI Journal Citation Reports® (2009)
Impact factor: 3.982	5-Year Impact Factor: 3.890
Immediacy index: 1.239	Cited half-life: 9.2 years

- now fully compliant with funding body mandates including NIH , Wellcome Trust, MRC and the British Heart Foundation. Read our FAQs

Take a look at our spotlight on Clinical Science Editor-in-Chief, R. Clinton Webb. Clinton talks about his life and work and the benefits of publishing in Clinical Science.

The interdependence of endothelin-1 and calcium: a review

ET-1 (endothelin-1) regulates a diverse array of physiological processes, including vasoconstriction, angiogenesis and cell proliferation, and most of its effects are associated with an increase in intracellular calcium concentrations. In this Review, Nathan Tykocki and Stephanie Watts describe the interactions between ET-1 and calcium, explore novel mechanisms involved in ET-1-mediated calcium signalling and outline some of the challenges ahead in this area of research.

My CS - have you signed up yet?

My CS is personal online area where you can create your own customized searching and alerting, save your favourite articles in your own filing cabinet and set up a distribution list to send information to colleagues!

log in or register now and start creating your My CS profile today! For more details see our My CS user guide